The rate of flushing anticoagulation locks into dual lumen dialysis catheters influences the formation of thrombus

  • Mrs Sandie Aguiar, Monash Medical Centre, Australia
  • Ms Joanne Kok, Monash Medical Centre, Australia
  • Ms Siew Eng Foo, Monash Medical Centre, Australia
  • The formation of thrombosis in dual lumen dialysis catheters remains a major problem that compromises dialysis adequacy, shortens the lifespan of an access, and can cause frustration to both patients and medical staff. During interdialytic periods, catheters are locked with varying concentrations of heparin or citrate based solutions as a prophylactic measure to deter the formation of a thrombus. Both solutions have different clinical side effects and have different economic costs.

    There is much discussion about which type of solution can deter the formation of a thrombus, but there is a lack of focus on the rate of infusion and how it influences the efficiency of anticoagulation. There is dearth of journals discussing the rate of infusing anticoagulant locks on the internet.

    During this presentation, a short video will be showed demonstrating how the rate of the flushing of a catheter can affect catheter leakage, and how circulating blood can enter the catheter at its tip. It is possible that there may be blood reflux into the catheter lumen when flushed.

    The information provided in this demonstration suggests that it may be beneficial to reduce the rate of infusing anticoagulant locks. This is irrespective of discussions relating to different types of anticoagulants, varying concentrations and cost effectiveness. However, further clinical studies are required to evaluate the results in clinical applications.