Calciphylaxis or Calcific Uraemic Arteriolopathy is a rare complication of Chronic Kidney Disease, difficult to treat and often resulting in high mortality rates.

This case study recounts the journey of one courageous person, challenged to the extreme by this complex condition, with a long history of elevated calcium phosphate product, resistant to treatment and inevitably, secondary hyperthyroidism. Painful tumours and lesions developed which took considerable time to diagnose correctly and the usual treatment options, as is often the case, were unsuccessful. Time was running out and with a leap of faith for all concerned, an experimental drug was commenced. This, combined with further surgical intervention, provided a favourable outcome.

This case serves as a reminder to all doctors and nurses who care for the End Stage Renal Failure population that we need to remain vigilant, observant and actively listen to our patients. Do not be afraid to become involved, instead, take up the challenge to identify the “unusual” and allow yourself to be inspired by your patients.